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Future clinical investigations may consider H 2 S and its related metabolic factors (such as L-cysteine, homocysteine, CSE, CBS, and 3-MST as relevant biomarkers for assessing the prognosis and risk of developing PH from CHD and COPD

Some studies demonstrated that ApoE4 homozygotes have a very high risk for Amyloid-related imaging abnormalities (ARIA) with both aducanumab and lecanemab and many providers do not administer these medications in ApoE4 homozygote carriers for this reason (Sperling et al., 2012

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